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. 2020 May 18;22(2):687–696. doi: 10.3892/mmr.2020.11158

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Effects of SOX4 knockdown on GC cell proliferation, migration, invasion and apoptosis. AGS and HGC-27 cells were transfected with sh-SOX4 or sh-NC. (A) mRNA and (B) protein expression levels of SOX4 in GES-1, AGS and HGC-27 cells. The transfection efficiency of sh-SOX4 was determined by (C) reverse transcription-quantitative PCR and (D) western blotting in AGS and HGC-27 cells. Effect of SOX4 knockdown on GC cell proliferation in (E) HGC-27 and (F) AGS cells. Effect of SOX4 knockdown on GC cell (G) apoptosis, (H) migration and (I) invasion. *P<0.05 vs. sh-NC. SOX4, sex-determining region Y-related high mobility group box 4; GC, gastric cancer; sh, short hairpin RNA; NC, negative control; OD, optical density.