Table VI.

Univariate and multivariate Cox regression analysis for recurrence-free survival.

	Univariate Cox regression			Multivariate Cox regression
Variables	P-value	HR	95% CI	P-value	HR	95% CI
Risk score (high/low)	0.009a	4.883	1.485–16.051	0.002a	2.895	1.491–5.621
Age (>60/≤60)	0.064	2.343	0.952–5.767
BMI	0.255
<25	Reference
≥25		0.533	0.092–3.074
Not reported		0.087	0.004–1.772
Race	0.403
Non-Asian	Reference
Asian		4.064	0.514–32.105
Not reported		1.065	0.034–33.341
Sex (Male/Female)	0.680	1.523	0.207–11.220
Hepatitis B or C	0.210
No	Reference
Yes		3.102	0.528–18.223
Cirrhosis	0.340
Non-cirrhosis	Reference
Cirrhosis		2.228	0.297–16.737
Not reported		0.291	0.037–2.284
Histologic grade	0.489
G1-2	Reference
G3-4		0.705	0.262–1.899
New tumor event	0.860
No	Reference
Yes		316078	0.000–3.495×1066
Pathologic stage	0.464
Stage I+II	Reference
Stage III+IV		1.896	0.638–5.632
Not reported		0.997	0.127–7.803
Cancer status	0.286
Tumor free	Reference
With tumor		2.632	0.323–21.431
Not reported		11.747	0.399–345.797
Family cancer history	0.242
No	Reference
Yes		0.726	0.147–3.588
Not reported		0.129	0.010–1.703
Residual tumor	0.749
R0		Reference
Non-R0		0.930	0.090–9.614
Not reported		0.321	0.015–6.981
Vascular invasion	0.039a			0.001a
Negative	Reference	Reference
Positive		10.023	1.408–71.326		2.398	1.104–5.210
Not reported		3.990	0.369–43.169		4.732	2.235–10.019

^aP<0.05. BMI, Body mass index; AFP, α fetoprotein; HR, Hazard ratio; CI, Confidence interval.