Figure 4. Loss of the REV-ERBs has differential effects on gene expression in BMDCs.
(A) mRNA analysis of BMDCs from WT or REV-ERBα KO mice to assess the expression of various pro-inflammatory cytokines, chemokines, and transcription factors. (n=3) (B) mRNA analysis of BMDCs from WT or REV-ERBβ KO mice to assess the expression of various pro-inflammatory cytokines, chemokines, and transcription factors. Data represents mean ± SEM. (n=3) B2M was used as the housekeeping control. Student’s two-tailed t-tests were performed for statistical analysis. *p<0.05, **p<0.01, ****p<0.0001.