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. 2020 Jul 4;416:117011. doi: 10.1016/j.jns.2020.117011

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Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 1 — (a) CD3+ and CD3 + CD4+ lymphocyte count after start of therapy with fingolimod until the hospitalization for Covid-19 in case 1 (b) anti spike protein S1 receptor binding domain (S1RBD) and anti-nucleocapsid (NP) IgG response to SARS-CoV-2 in patient 1 and 2 detected at 7,21,28,35 days after diagnosis. Dotted line: Cut off of anti-NP IgG positivity (=0.199). Continuous line: Cut off of anti-S1RBD IgG positivity (=1.000). Od450: optical density measurements using a microplate reader with a 450 nm filter.