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. 2020 Jun 30;11:663. doi: 10.3389/fgene.2020.00663

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Copyright © 2020 Wei, Lu, Lou, Shi, Mo, Shao, Ni, Zhang and Cheng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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mRNA expression patterns of the eight hub genes was verified with the Oncomine and GEO databases. (A) The Oncomine database shows the mRNA expression differences between various cancers and corresponding normal tissues. The threshold is shown at the bottom. The figure in the colored cell indicates the number of data sets satisfying the threshold. The red cells show that hub genes are overexpressed in tumor tissues, while the blue cells show that hub genes are downregulated in tumor tissues. (B,C) Boxplots show the expression of eight hub genes in gastric cancer and normal gastric tissues from GSE54129 and GSE13911 datasets. ***P < 0.001; **P < 0.01.