Table 1.
IC50 values for artesunate hybrid compounds
| S/no. | Drug/hybrid | IC50 (parasite strain) | Reference | |
|---|---|---|---|---|
| 1. | Artesunate | 6.3 nM (D10) | 31.2 nM (Dd2) | Singh et al. (2014) |
| 2. | Chloroquine | 21.8 nM (D10) | 140 nM (Dd2) | Singh et al. (2014) |
| 3. | Mefloquine/artesunate | 1.1 ng/ml (3D7) | 1.0 ng/ml (W2) | Varotti et al. (2008) |
| 4. | Primaquine/artesunate | 4.07 ng/ml (W2) | Boechat et al. (2014) | |
| 5. | Indoloquinoline/artesunate | 0.45 nM (NF54) | 0.42 nM (K1) | Wang et al. (2014) |
CQ-sensitive P. falciparum strains: D10, 3D7, and NF54; CQ-resistant strains: Dd2, W2, and K1