Table 4.
Subgroup Analyses by Location
| Esophageal | Total | FNA | FNB | P value |
|---|---|---|---|---|
| Sensitivity | 57.14% (95% CI, 18.41 to 90.10) | 0.00% (95% CI, 0.00 to 97.50) | 66.67% (95% CI, 22.28 to 95.67) | <0.001 |
| Specificity | 95.00% (95% CI, 75.13 to 99.87) | 93.33% (95% CI, 68.05 to 100.00) | 100.00% (95% CI, 47.82 to 100.00) | 0.391 |
| Positive Likelihood Ratio | 11.43 (95% CI, 1.52 to 85.74) | 0.00% | NA | NA |
| Negative Likelihood Ratio | 0.45 (95% CI, 0.19 to 1.07) | 1.07 (95% CI, 0.94 to 1.23) | 0.33 (95% CI, 0.31 to 1.03) | 0.832 |
| Positive Predictive Value | 80.00% (95% CI, 34.78 to 96.78) | 0.00% | 100.00% | <0.001 |
| Negative Predictive Value | 86.36% (95% CI, 72.80 to 93.74) | 93.33% (95% CI, 92.44 to 94.13) | 71.43% (95% CI, 44.64 to 88.57) | 0.13 |
| Accuracy | 85.19% (95% CI, 66.27 to 95.81) | 87.50% (95% CI, 61.65 to 98.45) | 81.82% (95% CI, 48.22 to 97.72) | 0.689 |
| Gastric | ||||
| Sensitivity | 70.71% (95% CI, 60.71 to 79.43) | 56.10% (95% CI, 39.75 to 71.53) | 81.03% (95% CI, 68.59 to 90.13) | <0.001 |
| Specificity | 100.00% (95% CI, 95.85 to 100.00) | 100.00% (95% CI, 90.97 to 100.00) | 100.00% (95% CI, 92.60 to 100.00) | NA |
| Positive Likelihood Ratio | NA | NA | NA | NA |
| Negative Likelihood Ratio | 0.29 (95% CI, 0.22 to 0.40) | 0.44 (95% CI, 0.31 to 0.62) | 0.19 (95% CI, 0.11 to 0.32) | 0.914 |
| Positive Predictive Value | 100.00% | 100.00% | 100.00% | NA |
| Negative Predictive Value | 75.00% (95% CI, 68.84 to 80.29) | 68.42% (95% CI, 60.52 to 75.38) | 81.36% (95% CI, 71.94 to 88.14) | 0.042 |
| Accuracy | 84.41% (95% CI, 78.38 to 89.30) | 77.50% (95% CI, 66.79 to 86.09) | 89.62% (95% CI, 82.19 to 94.70) | 0.025 |
| Duodenum | ||||
| Sensitivity | 50.00% (95% CI, 18.71 to 81.29) | 33.33% (95% CI, 4.33 to 77.72) | 75.00% (95% CI, 19.41 to 99.37) | 0.076 |
| Specificity | 100.00% (95% CI, 66.37 to 100.00) | 100.00% (95% CI, 29.24 to 100.00) | 100.00% (95% CI, 54.07 to 100.00) | NA |
| Positive Likelihood Ratio | NA | NA | NA | NA |
| Negative Likelihood Ratio | 0.50 (95% CI, 0.27 to 0.93) | 0.67 (95% CI, 0.37 to 1.17) | 0.25 (95% CI, 0.05 to 1.36) | 0.894 |
| Positive Predictive Value | 100.00% | 100.00% | 100.00% | NA |
| Negative Predictive Value | 64.29% (95% CI, 49.20 to 76.99) | 42.86% (95% CI, 29.87 to 56.91) | 85.71% (95% CI, 52.36 to 97.04) | 0.056 |
| Accuracy | 73.68% (95% CI, 48.80 to 90.85) | 55.56% (95% CI, 21.20 to 86.30) | 90.00% (95% CI, 55.50 to 99.75) | 0.098 |