TABLE 1.
Participant and Procedural Characteristics by Treatment Group
| Variable | Povidone-Iodine (n = 50) | BSS (n = 50) | P |
|---|---|---|---|
| Demographics | |||
| Sex | .221 | ||
| Male, n (%) | 17 (34%) | 23 (46%) | |
| Female, n (%) | 33 (66%) | 27 (54%) | |
| Age, years, mean ± SD | 6.62 ± 3.88 | 6.40 ± 3.36 | .805 |
| Weight, kg, mean ± SD | 23.5 ± 10.4 | 26.9 ± 13.4 | .153 |
| Medical history | |||
| Preexisting condition, yes, n (%) | 15 (30%) | 16 (32%) | .829 |
| Asthma, yes, n (%) | 4 (8%) | 6 (12%) | .505 |
| History of apnea, yes, n (%) | 4 (8%) | 4 (8%) | 1.000 |
| Preterm birth, yes, n (%) | 8 (16%) | 8 (16%) | 1.000 |
| Prior surgery, yes, n (%) | 27 (54%) | 32 (64%) | .309 |
| Before strabismus surgery, yes, n (%) | 8 (16%) | 19 (38%) | .013 |
| Before T&A surgery, yes, n (%) | 7 (14%) | 5 (10%) | .538 |
| Before BMT surgery, yes, n (%) | 7 (14%) | 3 (6%) | .182 |
| Before other surgeries, yes, n (%) | 15 (30%) | 10 (20%) | .248 |
| Preoperative measures | |||
| Any preoperative medications, yes, n (%) | 35 (70%) | 35 (70%) | 1.000 |
| Preoperative midazolam, yes, n (%) | 34 (68%) | 34 (68%) | 1.000 |
| Dose midazolam (all), median (IQR) | 7 (12) | 9 (10) | .709 |
| Dose midazolam if yes, median (IQR) | 10 (5) | 10 (3) | |
| Other preoperative medication, yes, n (%) | 1 (2%) | 2 (4%) | 1.000 |
| Preinstillation average breath duration, sec, mean ± SD | 1.75 ± 0.45 | 1.83 ± 0.49 | .357 |
| Preinstillation % expired sevoflurane, mean ± SD | 4.64 ± 1.46 | 4.40 ± 1.29 | .372 |
| Change in respiration after drop installation, yes, n (%) | 30 (60%) | 0 (0%) | < .001 |
BSS = balanced salt solution; SD = standard deviation; T&A = tonsillectomy and adenoidectomy; BMT = bilateral myringotomy; IQR = interquartile range