Table 3:
Associations between SLICC/ ACR Damage Index items and ethnicity: comparing African Americans and Caucasians ever smokers
| # of events among smokers | HR1 (95% CI) | p-value | |
|---|---|---|---|
| Any cataract ever | 176 | 1.42 (1.05,1.93) | 0.0240 |
| Retinal change OR optic atrophy | 40 | 0.92 (0.48,1.76) | 0.7994 |
| Cognitive impairment OR major psychosis | 52 | 0.65 (0.36,1.17) | 0.1510 |
| Seizures requiring therapy for 6 months | 19 | 0.82 (0.32,2.14) | 0.6896 |
| Cerebral vascular accident ever OR resection | 77 | 1.30 (0.82,2.06) | 0.2565 |
| Cranial OR peripheral neuropathy | 70 | 0.62 (0.37,1.04) | 0.0676 |
| Transverse myelitis | 3 | 3.70 (0.34,40.79) | 0.2858 |
| Estimated or measured GFR < 50% | 173 | 1.82 (1.33,2.48) | 0.0002 |
| Proteinuria 3.5g/24hrs | 56 | 2.97 (1.66,5.32) | 0.0002 |
| End-stage renal disease | 37 | 3.87 (1.8,8.3) | 0.0005 |
| Pulmonary hypertension | 86 | 2.25 (1.44,3.53) | 0.0004 |
| Pulmonary fibrosis | 60 | 1.02 (0.61,1.72) | 0.9385 |
| Shrinking lung | 1 | N/C | N/C |
| Pleural fibrosis | 25 | 0.99 (0.43,2.25) | 0.9737 |
| Pulmonary infarction OR resection | 2 | N/C | N/C |
| Angina OR coronary artery bypass | 48 | 0.60 (0.33,1.12) | 0.1092 |
| Myocardial infarction ever | 52 | 1.03 (0.59,1.81) | 0.9111 |
| Cardiomyopathy | 39 | 2.65 (1.34,5.21) | 0.0049 |
| Valvular disease | 22 | 1.23 (0.52,2.89) | 0.6390 |
| Pericarditis>6 months, OR pericardiectomy | 10 | 0.82 (0.23,2.97) | 0.7635 |
| Claudication x6 months | 24 | 1.17 (0.51,2.69) | 0.7097 |
| Minor tissue loss (pulp space) | 4 | 3.57 (0.36,35.57) | 0.2774 |
| Significant tissue loss ever | 11 | 1.14 (0.34,3.8) | 0.8325 |
| Venous thrombosis with swelling, ulceration, OR venous stasis | 19 | 0.81 (0.32,2.07) | 0.6635 |
| Infarction or resection of bowel | 83 | 0.56 (0.35,0.89) | 0.0143 |
| Mesenteric insufficiency | 3 | 1.83 (0.17,20.21) | 0.6226 |
| Chronic peritonitis | 1 | N/C | N/C |
| Stricture OR upper gastrointestinal tract surgery ever | 7 | 2.68 (0.5,14.29) | 0.2480 |
| Pancreatitis | 7 | 0.61 (0.11,3.23) | 0.5596 |
| Muscle atrophy or weakness | 21 | 1.10 (0.46,2.66) | 0.8254 |
| Deforming or erosive arthritis | 85 | 1.69 (1.09,2.63) | 0.0194 |
| Osteoporosis with fracture or vertebral collapse | 120 | 0.42 (0.28,0.63) | 0.0000 |
| Avascular necrosis | 76 | 2.50 (1.54,4.04) | 0.0002 |
| Osteomyelitis | 9 | 0.45 (0.11,1.86) | 0.2711 |
| Ruptured tendon | 29 | 1.55 (0.72,3.36) | 0.2618 |
| Scarring chronic alopecia | 33 | 4.66 (2.01,10.83) | 0.0003 |
| Extensive scarring or panniculum other than scalp and pulp space | 23 | 3.90 (1.44,10.57) | 0.0075 |
| Skin ulceration (not due to thrombosis) for more than 6 months | 16 | 1.31 (0.48,3.57) | 0.6003 |
| Premature gonadal failure | 27 | 0.64 (0.29,1.42) | 0.2712 |
| Diabetes | 59 | 3.12 (1.75,5.54) | 0.0001 |
| Malignancy (exclude dysplasia) | 99 | 0.82 (0.55,1.24) | 0.3527 |
1
Adjusted for sex, age at diagnosis, and years of education