TABLE 1.
All lncRNA regions where SNPs with p < 10–5 were found.
Regions | Position | Subject of the region | Subject associated gene | Subject position | Subject rationale | FANTOM-CAT gene category based on DHS support (DHS support in paranthesis) | FANTOM-CAT gene class based on coding potential and genomic context |
lncRNA-45 | chr3:177484653-177667012 | ENSG000 00231574 | RP11-91K9.1 | chr3:177534653-177617012 | LncRNA expression positively correlates with a BC high/moderate penetrance gene expression | e-lncRNA (enhancer) | lncRNA, intergenic |
lncRNA-49 | Chr6:33167311-33272766 | ENSG00 000232940 | chr4:33217311-33222766 | LncRNA expression positively correlates with a BC high/moderate penetrance gene expression | others (dyadic) | lncRNA, divergent | |
lncRNA-103 | chr8:17689552-17790170 | ENSG00 000253215 | chr8:17739552-17740170 | LncRNA expression positively correlates with a BC high/moderate penetrance gene expression | others (no) | ncRNA, divergent | |
lncRNA-26 | chr10:38403576-38551285 | ENSG00 000224761 | RP11-508N22.8 | chr10:38453576-38501285 | LncRNA higly expressed in breast tumor tissue | not in FANTOM-CAT db | not in FANTOM-CAT db |
lncRNA-82 | chr11:18571334-18681802 | ENSG000 00247595 | RP11-504G3.1 | chr11:18621334-18631802 | LncRNA moderately expressed in breast tumor tissue and its expression positively correlates with RAD50 expression | p-lncRNA (promoter) | lncRNA, divergent |
lncRNA-17 | chr14:101195747-101377368 | ENSG00 000214548 | MEG3 | chr14:101245747-101327368 | LncRNA higly expressed in breast tumor tissue | p-lncRNA (promoter) | lncRNA, intergenic |
lncRNA-75 | chr15:50597156-50714399 | ENSG0000 0244879 | GABPB1-AS1 | chr15:50646371-50650503 | LncRNA expression positively correlates with BRCA1 expression | p-lncRNA (promoter) | lncRNA, divergent |