Table 3.

Toxicity ≥ Grade 3 (CTCAE V 4.0) in Total Cohort

Toxicity	Grade 3	Grade 4	Grade 5	Grade 3, 4 or 5 Total (N=297)
Biochemical				73a (24.6%)
Bilirubin	35 (11.8%)	4 (1.3%)	0
AST/ALT	41 (13.8%)	0	0
ALP	2(0.6%)	0	0
Gastrointestinal
Biliary	1 (0.3%)	1 (0.3%)	1 (0.3%)	3 (1.0%)
Luminal GI toxicity	3 (1.0%)	0	1 (0.3%)	4 (1.3%)
Liver
Ascites	23 (7.7%)	0	0	23 (7.7%)
Classic RILD				0 (0%)
CP score decline ≥ 2 at 3 months after SBRT				34 (15.9%)
ALBI Grade increase at 3 months after SBRT				51 (21.2%)

Toxicity reported includes acute and late toxicity at least possibly attributable to SBRT.

^aSome patients had more than one kind of biochemical toxicity.