Table 4.

Association between low/non–low bone turnover and incident fractures in 641 Health ABC participants with chronic kidney disease

	Incident fracture, adjusted for hip BMD	Incident fracture, adjusted for spine BMD
	HR (95% CI)	HR (95% CI)
Non–low bone turnover	1.00 (Reference)	1.00 (Reference)
Low bone turnover
Unadjusted	0.96 (0.61-1.50)	0.97 (0.62-1.53)
Age-, sex-, race-, and site-adjusted	0.89 (0.54-1.40)	0.96 (0.61-1.50)
Fully adjusted	0.96 (0.60-1.53)	1.00 (0.63-1.60)

Fully adjusted for age, sex, race, site, BMI, SBP, HTN medications, eGFR, UACR, vitD25(OH)2, smoking status, alcohol use, diabetes, physical activity, and diuretics.

Abbreviations: BMD, bone mineral density; BMI, body mass index; eGFR, estimated glomerular filtration rate; Health ABC, Health Aging and Body Composition Study; HR, hazard ratio; HTN, hypertension; SBP, systolic blood pressure; UACR, urine albumin-to-creatinine ratio.