TABLE I.
Studies Included in the Review of the Epidemiology of Kaposi Sarcoma Among Children and Adolescents in sub-Saharan Africa.
| Author, Year Published | Study Year(s) | Location | Pediatric Study Sample Size (N) | Incidence of Kaposi sarcoma among children per patient-years | HIV-specific population | Prevalence of Kaposi sarcoma among children | HIV-specific population | Method of Diagnosis |
|---|---|---|---|---|---|---|---|---|
| Mbulaiteye, et al.[24], (2006) | 1989-2002 | Kampala, Uganda | 407 | 160/100,000 | Yes | -- | -- | Not described |
| Chintu, et al.[25], (1995) | 1980-1992 | Lusaka, Zambia | Population estimate | 75.7/100,000 | Yes | 0.04/100,000 | No | Histopathology |
| Rohner, et al.[26], (2014) | 2004-2010 | Southern Africa (Botswana, Malawi, Lesotho, South Africa, Zambia, Mozambique, Zimbabwe) | 13,859 | 59/100,000 | Yes | -- | -- | Both clinical and histopathology |
| Ziegler, et al.[27], (1996) | 1992-1993 | Entebbe, Uganda | Population estimate | 8/100,000 | Yes | -- | -- | Histopathology |
| Parkin, et al.[28], (2010) | 1991-1995 | Kampala, Uganda | Population estimate | 6.26/100,000 | No | -- | -- | Histopathology |
| Wabinga, et al.[29], (2000) | 1991-1997 | Kyadondo County, Uganda | Population estimate | 5.35/100,000 | No | -- | -- | Histopathology |
| Parkin, et al.[28], (2010) | 2002-2006 | Kampala, Uganda | Population estimate | 4.46/100,000 | No | -- | -- | Histopathology |
| Carreira, et al.[30], (2014) | 2009-2010 | Beira, Mozambique | Population estimate | 2.85/100,000 | No | -- | -- | Histopathology |
| Meireles, et al.[31], (2014) | 2007 | Maputo City, Mozambique | Population estimate | 2.05/100,000 | No | -- | -- | Not described |
| Chokunonga, et al.[32], (2014) | 2010-2012 | Harare, Zimbabwe | Population estimate | 1.47/100,000 | No | -- | -- | Both clinical and histopathology |
| Echimane, et al.[33], (2000) | 1995-1997 | Abijan, Ivory Coast | Population estimate | 0.1/100,000 | No | -- | -- | Both clinical and histopathology |
| Makata, et al.[34], (1996) | 1979-1994 | Nakuru, Kisumu, and Eldoret, Kenya | Population estimate | 0.09/100,000 | No | -- | -- | Histopathology |
| Athale, et al.[35], (1995) | 1981-1991 | Lusaka, Zambia | Population estimate | 0.03/100,000 | No | -- | -- | Histopathology |
| Cox, et al.[36], (2013) | 2003-2009 | Lilongwe, Malawi | 2,241 | -- | -- | 3,200/100,000 | Yes | Both clinical and histopathology |
| Tukei, et al.[37], (2011) | 2004-2008 | Kampala, Uganda | 6,530 | -- | -- | 1,513/100,000 | Yes | Histopathology |
| Ahmed, et. al.[38], (2012) | 1998-2007 | Zaria, Nigeria | 885 | -- | -- | 680/100,000 | Yes | Histopathology |
| Median Sample Size* | 2,241 | |||||||
| Median Incidence (General Population) | 2.05/100,000 | N/A | ||||||
| Median Incidence (HIV-infected Population) | 67.4/100,000 | 1,513/100,000 |
*
Among studies with reported denominators.