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RSV increases the expression of SIRT1 in endothelial cells and is suppressed by EX-527 (n = 3). A, B, Compared with the Vehicle group, RSV significantly increased the expression of SIRT1; the expression of SIRT1 in the RSV + LPS group was significantly higher than that of Vehicle + LPS group. C, D, The expression of SIRT1 in the RSV + LPS + EX-527 group was lower than that of the RSV + LPS group; (A, C) is Western blot, and (B, D) is quantitative. *P < 0.05, **P < 0.01.
