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RSV reduces the expression of (A) MCP-1 mRNA, (B) ICAM-1 mRNA, and (C) VCAM-1 mRNA in LPS-induced endothelial cells and is suppressed by EX-527 (n = 3). In the RSV + LPS group, the expression levels of MCP-1 mRNA, ICAM-1 mRNA, and VCAM-1 mRNA were significantly lower than those in the Vehicle + LPS group. The expression levels of MCP-1 mRNA, ICAM-1 mRNA, and VCAM-1mRNA in the RSV+ LPS + EX-527 group were higher than in the RSV + LPS group. *P<0.05, **P<0.01, ***P<0.001.
