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RSV increases the expression of SIRT1 in AD of mice and is suppressed by EX-527 (n = 20 per group). Compared with the AD + Vehicle group, SIRT1 expression in the aorta of mice was significantly increased in the AD + RSV group, while SIRT1 expression in the AD + RSV + EX-527 group was lower than in the AD + RSV group. A is Western blot, and (B) is quantitative. **P < 0.01, ***P < 0.001.
