Average radial concentration distribution, ϕ(r), of hydrophobic core, PEG, and ibuprofen. The concentration profiles are shown after ibuprofen loading for the nanogel core (ϕ′nGel), ibuprofen (ϕIBU), corona PEG chains (ϕ′PEG), and the nanogel core combined hydrophobic copolymer arm segments (ϕ′nGel–HCP) for the four systems under study.