Table 4:
Overview of relevant studies on muira puama and zinc in the treatment of ED
| Muira Puama | |||
|---|---|---|---|
| Mechanism of Action (MOA): Increased NOS expression | |||
| Author | Study Type | Outcome Measure | Results |
| Ferrini et al. (2015) | In vitro rat model | NOS expression | Rats treated with muira puama had increased age-related erectile function compared with those treated with PDE5i therapy |
| Waynberg et al. (2000) | Survey | Independent sexual satisfaction questionnaire | Muira puama increased frequency and intensity of sexual thoughts and improved ability to achieve orgasm |
| Nguyen et al. (2018) | Prospective study | IIEF score | Treatment with Revactin improved erectile function as compared to baseline |
| Zinc | |||
| MOA: No clear mechanism of action | |||
| Prasad et al. (1995) | Cross-sectional study | Serum testosterone | Supplemental zinc increases serum testosterone levels and improves hypogonadal symptoms in men with zinc-poor diets |