Table 4.
Genotyping analysis of common complement component polymorphisms in 725 patients without DCI and 169 patients with DCI
| Gene | Allele | SNP ID | No DCI | DCI | OR (95%CI) | aOR (95%CI) | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| AA | AB | BB | AA | AB | BB | |||||
| C3 | C/T | rs1047286 | 432 | 214 | 28 | 103 | 47 | 7 | 0.93 (0.67–1.30) | 0.95 (0.67–1.33) |
| C3 | C/G | rs223019 | 467 | 222 | 29 | 113 | 49 | 7 | 1.11 (0.80–1.53) | 1.10 (0.79–1.53) |
| C5 | A/G | rs17611 | 152 | 334 | 239 | 27 | 91 | 51 | 1.09 (0.78–1.52) | 1.10 (0.79–1.55) |
Allele in bold is used for analysis
aOR adjusted odds ratio (adjusted for gender, age at time of ictus, and WFNS grading scale on admission), CI confidence interval, DCI delayed cerebral ischemia, OR odds ratio, SNP single nucleotide polymorphism