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. 2019 Dec 6;11(4):776–788. doi: 10.1007/s12975-019-00753-4

Fig. 4.

Fig. 4

NSC EV treatment inhibits cerebellar herniation in high midline shift animals. Mid-sagittal T2W MR images depicting bony landmarks utilized to discern degree of cerebellar herniation in non-treated (a) and NSC EV–treated (b) animals. SLL: skull length line, TTL: transtentorial line, FML: foramen magnum line, TTX: transtentorial line to rostral ventral cerebellum, FMX: caudoventral cerebellum to foramen magnum line. There is a significant degree of caudal transtentorial herniation (CTH = TTX/SLL) in between non-treated animals (c, p = 0.0284) with HMLS and LMLS, while there is not in NSC EV–treated animals (d, p = 0.0664). Additionally, there is a significant degree of foramen magnum herniation (FMH = FMX/SLL) between HMLS and LMLS non-treated animals (e, p = 0.0141) while there is not in NSC EV–treated (f, p = 0.1940)