Table 4.
Correlations of inflammatory markers with β-amyloid and tau pathology. Spearman’s rank correlations (r) of amyloid-β (Aβ) and tau pathology with Iba1 and GFAP are illustrated. *p < 0.05, **p < 0.01, **p < 0.001, $approaching significance. N.S. not significant
Marker | Soluble Aβ | Fibrillar Aβ | Oligomeric tau | Phosphorylated tau | Total tau | ||
---|---|---|---|---|---|---|---|
MOAB | OC | TOC-1 | PHF-1 | AT-8 | CP-13 | HT-7 | |
Iba1 | N.S. | N.S. | N.S. | N.S. | N.S. | N.S. | N.S. |
GFAP | $p = 0.062 | ***r = 0.51 ± 0.13 | *r = 0.34 ± 0.15 | **r = 0.38 ± 0.14 | ***r = 0.48 ± 0.14 | *r = 0.35 ± 0.14 | **r = 0.53 ± 0.13 |