Table 1.
Patient cohort | Patient without prim outcome | Patient with prim outcome | Healthy controls | Stroke register 2011 | |
---|---|---|---|---|---|
N = 211 | N = 157 | N = 54 | N = 53 | N ≈ 25,000 | |
Age at inclusion (years) | 72.3 ± 8.2 | 71.5 ± 8.2 | 74.4 ± 7.9* | 70.4 ± 7.8 | 75.9 |
Female (n (%)) | 89 (42%) | 72 (46%) | 17 (31%) | (42%) | 48% |
Medical history at inclusion | |||||
Hypertension (n (%)) | 139 (66%) | 101 (64%) | 39 (72%) | 61% | |
Diabetes (n (%)) | 32 (15%) | 19 (12%) | 13 (24%)* | 24% | |
Active smoker (n (%)) | 38 (18%) | 29 (19%) | 8 (14%) | 13% | |
Previous IS/TIA (n (%)) | 53 (25%) | 35 (22%) | 18 (33%) | 37% | |
IHD (n (%)) | 38 (18%) | 26 (17%) | 13 (24%) | ||
TIA as index event (n (%)) | 72 (34%) | 54 (34%) | 17 (31%) | ||
NIHSS | 0 (0–1) | 0 | 0 | ||
BMI at inclusion (kg m−2) | 25.8 ± 3.8 | 25.9 ± 3.8 | 25.5 ± 3.9 | ||
Hemoglobin (g l−1) | 141 ± 13 | 141 ± 13 | 141 ± 15 | 137 ± 10 | |
Leukocyte count (× 109 l−1) | 6.9 (5.9–8.9) | 6.9 | 6.9 | 5.0 (4.3–5.5) | |
Platelet count (× 109 l−1) | 214 (181–262) | 213 | 214 | 216 (184–235) | |
Hs-CRP (mg l−1) | 2.5 (0.9–6.4) | 2.55 | 2.40 | 0.72 (0.27–1.14) | |
P-glucose (mM) | 6.4 (5.6–7.7) | 6.3 | 6.5 | 5.4 (5.0–5.6) | |
Creatinine (μM) | 80 (70–93) | 79 | 86* | 70 (63–84) | |
eGFR (ml min−1 1.73m−2) | 79 ± 20 | 80 ± 19 | 76 ± 22 | 89 ± 14 | |
LDL-cholesterol (mM) | 3.2 ± 0.9 | 3.3 ± 1.0 | 3.0 ± 0.8* | 3.6 ± 0.8 |
IS, ischemic stroke; TIA, transient ischemic attack; IHD, ischemic heart disease; NIHSS, National Institute of Health Stroke Scale; BMI, body mass index; eGFR, estimated glomerular filtration rate
* signifies statistical probability p < 0.0001