Fig. 2.

Mean cumulative amount of finasteride permeated through human scalp skin over 24 h: (a) at 32°C; (b) at 45°C. The inset graphs show an expanded image of the delivery between 0 to 4 h. Finasteride was applied (0.5 mL cm⁻²) to the skin surface in a previously equilibrated saturated suspension for each vehicle. Vehicles tested were dimethyl isosorbide (DMI), diisopropyl adipate (DPA), isopropyl alcohol (IPA), propylene glycol (PG) and Transcutol P® (TP). * indicates significant differences in finasteride delivery at 45°C. All points are mean + SEM of n = 6 diffusion cells