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. 2020 May 31;37(6):112. doi: 10.1007/s11095-020-02822-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — (a) The amount of finasteride recovered from the stratum corneum (SC), epidermis, hair follicles, dermis and receiver fluid at the end of the 24 h finite dose permeation study from IPA:PG (1:1) binary system; (b) mean cumulative amount of finasteride permeated through human scalp skin over 24 h from IPA:PG (1:1) binary system. Experiments were conducted at 32°C with and without ST solution producing heat (~ 43°C) for Ca. 20 & 30 mins (ST 20 & ST 30 respectively) and at 45°C (without ST). All bars are mean + SEM of n = 6 diffusion cells. * denotes significant difference in the amount of drug recovered compared to the control (32°C, no additional heat)