Table 5.
Examples of quotations: injectable route of administration
| Examples of quotations about the injectable route of administrationa | ||
|---|---|---|
| Positiveb | Negativeb | |
| 1. Healthcare provider visits | Obviously a 3 monthly shot would fit nicely with routine clinic visits | Having to go to the clinic every few weeks for a shot would be more invasive to me than taking a pill per day I think |
| 2. Pain | Oddly, this week's Rilpivirine shot wasn't painful. I was surprised | …the Rilpivirine stick can be painful |
| 3. Needles | I don't mind needles so I'm really interested in the injectable | I too have a terrible fear of needles…you'd think I'd be used to it. NO!!!! I always have to be reading something so I can be distracted and I never, ever look. At the needle or the draw itself |
| 4. Strength of dosage | None | …and kind of scares me to know that if I miss the dose it would be the equivalent of missing 7/15/30 pills |
| 6. Access | It would also be nice not to have, in my case, the once every 90-day concern that the three-month supply arrives by post | …travelling…every few weeks is not practical for me or my job because HIV meds/care is only dispensed in hospital clinics, not the pharmacy's or smaller regional hospitals. It just equals more unpaid days off work… |
| 7. Stockpiling | None | I also like having some control, hence building up a surplus of pills helps in this respect |
| 8. Traveling | I find the research pertaining to long-acting injectable antiretrovirals really interesting, and potentially these could make a real difference to my daily life. I travel a lot and remembering to take the pills with me, dosing the right way across time zones and entering countries that have entry barriers could all be made much easier! | what if I want to take a long vacation but I need this shot once a month, this might not be practical for some of us |
| 9. Food requirements | The current downfall of rpv is the meal requirement. An injectable would negate that issue | My issue is the daily food requirement during this induction phase |
| 12. Frequency of doses | Personally, I'll be happy to toss my current HIV meds out the window the day they finally develop that once-a-month drug even if it is an injectable | I would consider it an option only if it were a one-year shot. But, since I only need to go to my ID clinic once or twice a year, and they give me a 6–12 month supply of medicine, why bother? |
| 13. Schedule issues | I honestly would prefer taking an injection every month instead of worrying about my next pill's time. This one sounds hopeful! | But it would have to have a back-up plan (daily oral version) for those times when it doesn't fit exactly with schedules |
| 14. Control of dosing | And with the control of daily dosing comes higher risks for mishaps. I don’t see injections as giving up any control one has with their health. It is a way to get 4 or 8 weeks of treatment in one sitting | I would rather take my daily pill, long lasting shots and implants would drive me crazy, i would hate not having the "feeling" of control over this |
| 15. Adherence concerns | An injection would … massively help with adherence in communities where that is a particular problem | kind of scares me to know that if I miss the dose it would be the equivalent of missing 7/15/30 pills (or whatever the substitution is) |
| 21. Privacy and confidentiality (stigma) | …monthly injections might have some advantages. For patients who need to travel (for work) to countries that may give you trouble if they find your meds at the border check | None |
| 23. Visible reminder of HIV status or treatment | Nonetheless, monthly injections would be a great improvement, sort of a "one and done" each month, and no pill containers would be nice and so would not seeing the Atripla container in the medicine chest | None |
| 24. Emotional impact | I would happy dance the nerdiest nerd dance all over town for days if I could get an injection every few months and not have to bother with daily pills | I’m a bit anxious about these injections |
| 25. Ease of use | The injection—l just thought it would be easier | None |
| 26. Convenience | Injectable that can be taken once a month or every couple months, still in development. If it works, would be super convenient for someone like me | Personally the Long lasting injections (or the idea of them) is not interesting for me or at least I simply don't consider it practical |
| 27. Unspecified preference | That's the greatest news I ever read about treatment improvement! | None |
aConcept codes 5, 10, 11, 16, 17, 18, 19, 20, and 22 are omitted from this table because there were no statements on the injectable route of administration that received these codes
bThe sentiment of each quotation (i.e., positive, negative, or neutral) was coded from the patient’s point of view, which may diverge from the clinical, regulatory, or payer perspective in some situations