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. 2020 Apr 10;36(7):761–777. doi: 10.1007/s12264-020-00490-x

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© The Author(s) 2020

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Fig. 7 — Meclizine redirects metabolic flux toward glycolysis. A, B Pretreatment with meclizine did not significantly change ATP levels (A) or ADP/ATP ratios (B). C Representative images of LDH staining (note the stronger staining in the meclizine group than in the control group, and in the meclizine pretreatment ONC group than in the ONC group; histochemical ratings in Table S2). Scale bar, 100 μm. D LDH activity in the meclizine treatment and the ONC/meclizine groups. E Effects of pretreatment with meclizine on ONC_CCCP/CON_CCCP and ONC_2DG/CON_2DG in injured optic nerves.