Table 2.
No | Age | Sex | Event | Time to event (months) | Details | MLD (Gy) | Lung V20 (%) | MHD (Gy) | PA V35 (Gy) |
---|---|---|---|---|---|---|---|---|---|
1 | 58 | F | G2 RP | 9 | Symptomatic; medication required | 12.3 | 21.8 | 8.5 | 75.4 |
2 | 59 | F | G2 RP | 2 | Symptomatic; medication required | 13.9 | 20.8 | 18.4 | 99.6 |
3 | 44 | F | G2 RP | 9 | Symptomatic; medication required | 11.8 | 21.6 | 29.4 | 94.1 |
4 | 55 | F | G2 RP | 5 | Symptomatic; medication required | 8.3 | 11.4 | 10.3 | 69.5 |
5 | 50 | F | G2 RP | 3 | Symptomatic; medication required | 16.7 | 35.3 | 44.9 | 100 |
6 | 72 | M | G2 RP | 5 | Symptomatic; medication required | 11.4 | 22.8 | 5.0 | 32.3 |
7 | 63 | M | G2 RP | 2 | Symptomatic; medication required | 5.5 | 9.6 | 14.2 | 94.7 |
8 | 59 | F | G2 RP | 2 | Symptomatic; medication required | 17.2 | 37.0 | 33.6 | 100 |
G3 Carditis | 18 | Constrictive pericarditis; pericardiotomy required | |||||||
9 | 57 | F | G2 RP | 2 | Symptomatic; medication required | 16.3 | 36.6 | 39.8 | 100 |
G5 Carditis | 40 | Heart failure due to constrictive pericarditis | |||||||
10 | 66 | M | G3 RP | 1 | Hospitalization required | 8.5 | 12.9 | 9.3 | 53.5 |
11 | 70 | F | G3 RP | 6 | Hospitalization required | 12.1 | 26.1 | 18.2 | 85.4 |
12 | 82 | M | G3 RP | 2 | Hospitalization required | 16.3 | 27.7 | 34.3 | 89.9 |
G3 Carditis | 8 | Constrictive pericarditis and effusion; conservatively managed | |||||||
13 | 76 | M | G5 RP | 2 | Respiratory failure due to refractory RP | 17.0 | 33.7 | 14.6 | 100 |
14 | 56 | F | G3 Carditis | 9 | Constrictive pericarditis; pericardiotomy required | 15.3 | 33.0 | 40.7 | 100 |
Data were described as equivalent 2-Gy fractions (EQD2) using the LQ model with α/β = 3 Gy.
MLD mean lung dose, V20 percentage volume receiving at least 20 Gy, MHD mean heart dose, G grade, RP radiation pneumonitis, PA pulmonary artery, V35 percentage volume receiving at least 35 Gy.