Table 3.
Multivariate analysis of clinical factors and dosimetric parameters predicting ≥ grade 2 radiation pneumonitis among patients with thymic epithelial tumors after radiotherapy.
| HR (95% CI) | p value | |
|---|---|---|
| Age (continuous) | 1.06 (1.01–1.11) | 0.022 |
| Sex | 0.99 (0.13–7.84) | 1.00 |
| Smoking history | 1.77 (0.22–14.4) | 0.59 |
| Surgery | 1.01 (0.24–4.19) | 0.99 |
| Chemotherapy | 0.54 (0.13–2.19) | 0.39 |
| Steroid therapy | 5.69 (1.27–25.4) | 0.023 |
| Lung V35 | 1.07 (0.97–1.16) | 0.17 |
| PA V35 | 1.04 (1.01–1.07) | 0.007 |
| LA V35 | 0.97 (0.93–1.02) | 0.22 |
| LV V35 | 1.02 (0.99–1.06) | 0.15 |
HR hazard ratio, 95% CI 95% confidence interval, The V35 volume (%) of each structure receiving at least 35 Gy, PA pulmonary artery, LV left ventricle, LA left atrium.