TABLE 2.
Associations between total number of sensory impairments at baseline and risk of incident all‐cause dementia, Alzheimer's disease, and vascular dementia in the GEM Study (2000‐2008)
| All‐cause dementia (n = 321) | Alzheimer's disease (n = 220) | Vascular dementia (n = 86) | ||||
|---|---|---|---|---|---|---|
| Number of sensory impairments | Hazard ratio (95% CI)a | P | Hazard ratio (95% CI)a | P | Hazard ratio (95% CI)a | P |
| No sensory impairment | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) | |||
| Single sensory impairment | 1.11 (0.86‐1.44) | .43 | 1.10 (0.80‐1.50) | .58 | 1.19 (0.73–1.95) | .48 |
| Dual sensory impairment | 1.86 (1.25‐2.76) | .002 | 2.12 (1.34‐3.36) | .001 | 1.22 (0.52–2.89) | .65 |
| Test for trend | .009 | .01 | .46 | |||
CI, confidence interval.
a
Models adjusted for age, sex, race, education, income, body mass index, alcohol intake, smoking status, physical activity, cardiovascular disease, cerebrovascular disease, diabetes, hypertension, clinic site, treatment status, and APOE.