Table 3. Summary of UNOS guidelines for LT in NET.
Common criteria with Milan-NET |
Histologic grade of G1 or G2 |
Gastro-entero-pancreatic origin tumors with portal system drainage |
Resection of primary and extra-hepatic disease without recurrence >6 months |
Tumor replacement <50% of the liver volume |
Recipient age <60 years |
Additional criteria |
Unresectable liver metastasis |
Radiographic characteristics of NET of the liver lesions |
Negative metastatic workup by PET scan |
Lack of extrahepatic tumor recurrence during the past 3 months |
In the presence of positive findings for lymph node metastases by PET scan, the finding should become negative for 6 months before re-listing |
In the presence of extrahepatic solid organ metastases (i.e., lungs or bones), the case will be permanently delisted |
NET, neuroendocrine tumors; PET, positron emission tomography.