FIGURE 1.

Reduced expression of BRCA2 in the aorta of the atherosclerosis animal model and in oxLDL‐treated HUVECs. (a) BRCA2 qPCR data on RNA isolated from aorta of ApoE^−/− mice fed high‐fat diet versus control diet. N = 6/group. ***p < .001 versus control. (b) BRCA2 qPCR performed on RNA isolated from oxLDL (0, 5, 10, 20, 50, and 100 μg/ml for 24 hr)‐treated HUVECs. N = 3–4 in triplicate. *,**p < .05, .01 versus control. (c) BRCA2 qPCR performed on RNA isolated from oxLDL (100 μg/ml for 0, 6, 12 and 24 hr)‐treated HUVECs. N = 3–4 in triplicate. **,***p < .01, .001 versus control