Figure 3.

Docked poses of A. compound 29 (with binding energy of −8.9 kcal/mol), B. compound 33a (with binding energy of −8.7 kcal/mol) and C. compound 34a (with binding energy of −10.0 kcal/mol) shown by green carbon atoms in the serotonin 5-HT7 receptor target shown by secondary structure elements and grey carbon atoms for select residues. Key quaternary N – Asp salt bridges are depicted by the pink dashed lines, H-bonding interactions by the yellow dashed lines, π-π stacking by the blue dashed lines and corresponding π-cation interactions by the green dashed lines.