. Author manuscript; available in PMC: 2021 Aug 1.

Published in final edited form as: Bioorg Med Chem. 2020 Jun 5;28(15):115578. doi: 10.1016/j.bmc.2020.115578

Table 5.

Functional activity of compounds 29 and 34a in cAMP assays

Compound	Assay mode	Agonist^a EC₅₀(μM)	Antagonist^a IC₅₀ (μM)
29	agonist	>10	-
29	antagonist	-	0.125
34a	agonist	>10	-
34a	antagonist	-	0.26
Serotonin	agonist	0.07	-
Spiperone.HCl	antagonist	-	0.31

Experiments performed in duplicate