Table 2.
Group | REV Viremiab |
REV Sheddingc |
||||||
---|---|---|---|---|---|---|---|---|
7d | 14 | 21 | 28 | 7 | 14 | 21 | 28 | |
rMDV-Cas-gLTR1/6+REV | 2/10 | 1/10 | 0/10 | 0/10 | 0/10 | 0/10 | 0/10 | 0/10 |
rMDV+REV | 6/10 | 4/10 | 1/10 | 0/10 | 0/10 | 0/10 | 0/10 | 0/10 |
Mock | 0/10 | 0/10 | 0/10 | 0/10 | 0/10 | 0/10 | 0/10 | 0/10 |
Chickens were inoculated with rMDV-Cas9-gLTR1/6 or the WT parental MDV (rMDV) at 1 day of age, and challenge with REV at 8 days of age. Plasmas and vaginal swabs were collected after REV challenge for viremia and viral shedding detection.
Ratios of REV viremic birds to total detected birds.
Ratios of REV shedding birds to total detected birds.
Days after REV challenge.