Table 3.
Transfusion Scenario 2: Non-LR, WB transfusion between recipient and donor who share few antigens/alleles.
| HLA Locus | Recipient C HLA Type WBC: 4.9 × 103/μl | Donor C HLA Type WBC: 6.1 × 103/μl | No. of distinct antigens/alleles detected at locus | Recipient and donor antigens/alleles detected in 10 unit transfusion scenario | Recipient and donor antigens/alleles detected in 2 unit transfusion scenario | Recipient and donor antigens/alleles detected in 1 unit transfusion scenario | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| R* | D** | R | D | R | D | ||||||
| A | *02:01 | *23 | *02:02 | *68 | 4 | *23 | *02:02, *68 | *23 | *02:02, *68 | *23 | *02:02, *68 |
| B | *15:01 (B62) | *57 | *07 | *15:03 (B72) | 4 | *15:01, *57 | *07, *15:03 | *15:01, *57 | *07, *15:03 | *15:01, *57 | *07, *15:03 |
| C | *03:03 (C9) | *06 | *07 | *12 | 4 | *03:03, *06 | *07, *12 | *03:03, *06 | *07, *12 | *03:03, *06 | None |
| DRB1 | *07 | *14 | *03:01 (DR17) | *15 | 4 | *07, *14 | *03:01, *15 | *07, *14 | *03:01, *15 | *07, *14 | *03:01, *15 |
| DRB3/4/5 | DRB4 *01:03 N | DRB3 *02 | DRB3 *02 | DRB5 *01 | 3 | DRB4 *01:03 N, DRB3 *02 (I***) | DRB5*01 DRB3 *02 (I) | DRB4 *01:03 N, DRB3 *02 (I) | DRB5*01 DRB3 *02 (I) | DRB4 *01:03 N, DRB3 *02 (I) | DRB5*01 DRB3 *02 (I) |
| DQA1 | *01:04 | *02:01 | *01:02 | *05:01 | 4 | *01:04, *02:01 | *01:02, *05:01 | *01:04, *02:01 | *01:02, *05:01 | *01:04, *02:01 | *01:02, *05:01 |
| DQB1 | *03:03 (DQ9) | *05 | *02 | *06 | 4 | *03:03, *05 | *02, *06 | *03:03, *05 | *02, *06 | *03:03, *05 | *02, *06 |
| DPA1 | *01:03 | *01 | *01:03 | *02 | 2 | *01:03 (I) | *01:03 (I) | *01:03 (I) | *01:03 (I) | *01:03 (I) | *01:03 (I) |
| DPB1 | *04:01 | XX | *01:01 | *4:01 | 2 | *04:01 (I) | *04:01 (I), *01:01 | *04:01 (I) | *04:01 (I), *01:01 | *04:01 (I) | *04:01 (I), *01:01 |
R=recipient allele detected based on positive recipient-specific wells.
D=donor allele detected based on positive donor-specific wells.
I=indeterminant; DNA source could not be determined due to recipient and donor sharing antigen/allele at that locus.