Table 4.
Transfusion Scenario 3: Non-LR, WB transfusion between recipient and donor who share several antigens/alleles.
HLA Locus | Recipient C HLA Type WBC: 6.1 × 103/μl | Donor C HLA Type WBC: 5.3 × 103/μl | No. of distinct antigens/alleles detected at locus | Recipient and donor antigens/alleles detected in 10 unit transfusion scenario | Recipient and donor antigens/alleles detected in 2 unit transfusion scenario | Recipient and donor antigens/alleles detected in 1 unit transfusion scenario | |||||
---|---|---|---|---|---|---|---|---|---|---|---|
R* | D** | R | D | R | D | ||||||
A | *01 | *68:01 | *01 | *68:02 | 3 | *01 (I***) | *01 (I), *68:02 | *01 (I), | *01 (I), *68:02 | *01 (I), *68:01 | *01 (I) |
B | *08 | *57 | *08 | *15:10 (B71) | 3 | *57, *08 (I) | *15:10, *08 (I) | *57, *08 (I) | *15:10, *08 (I) | *57, *08 (I) | *15:10, *08 (I) |
C | *06 | *07 | *03:04 (C1O) | *07 | 3 | *06, *07 (I) | *03:04, *07 (I) | *06, *07 (I) | *03:04, *07 (I) | *06, *07 (I) | *07 (I) |
DRB1 | *03:01 (DR17) | *07 | *03:01 (DR17) | XX | 2 | *07, *03:01 (I) | *03:01 (I) | *07, *03:01 (I) | *03:01 (I) | *07, *03:01 (I) | *03:01 (I) |
DRB3/4/5 | DRB3 *01 | DRB4 *01:03 N | DRB3 *01 | DRB3 *02 | 3 | DRB4 *01:03 N, DRB3 *01 (I) | DRB3*02, DRB3 *01 (I) | DRB4 *01:03 N, DRB3 *01 (I) | DRB3*02, DRB3 *01 (I) | DRB4 *01:03 N, DRB3 *01 (I) | DRB3 *01 (I) |
DQA1 | *02:01 | *05 | *05:01 | *05 | 2 | *02:01, *05 (I) | *05/05:01 | *02:01, *05 (I) | *05/05:01 | *02:01, *05 (I) | *05/05:01 |
*DQB1 | *02 | *03:03 (DQ9) | *02 | XX | 2 | *02 (I), *03:03 | *02 (I) | *02 (I), *03:03 | *02 (I) | *02 (I), *03:03 | *02 (I) |
DPA1 | *01:03 | *01 | *01:03 | *02 | 2 | *01:03/*01 (I) | *02, *01:03 (I) | *01:03/ *01 (I) | *01:03 (I) | *01:03/*01 (I) | *01:03 (I) |
DPB1 | *04:01 | XX | *01:01 | *04:02 | 3 | *04:01 | *01:01, *04:02 | *04:01 | *01:01, *04:02 | *04:01 | *01:01, *04:02 |
R=recipient allele detected based on positive recipient-specific wells.
D=donor allele detected based on positive donor-specific wells.
I=indeterminant; DNA source could not be determined due to recipient and donor sharing antigen/allele at that locus.