Fig. 3.
dCas9-mediated biosensing assays. (A) dCas9/sgRNA-SG I-based strategy for MRSA detection. (B) Paired-dCas9 (PC) reporter system for dsDNA detection. (Reprinted with permission from Zhang et al. (2017). Copyright, 2017; American Chemical Society). (C) RCA-CRISPR-split-HRP (RCH) system for miRNA detection. (Reprinted with permission from Qiu et al. (2018). Copyright, 2018; American Chemical Society).