Table 1. Characteristics of the study mice.

Characteristics	na	Mean ± SD	Median (25th, 75th)	Correlation with Cystatin C		Correlation with Cystatin C (Cst3) mRNAb
				r	p	r	p
Body weight, g	120	32.4 ± 7.4	31.5 (26.3, 37.3)	−0.014	0.88	0.028	0.80
Plasma cystatin C, ng/mL	109	535.5 ± 137.5	515.1 (427.7, 629.5)	1.000	NA	0.500	1.22 x 10−06
Blood urea nitrogen, mg/dL	120	14.9 ± 5.0	14.3 (11.9, 16.7)	−0.079	0.41	−0.097	0.38
Urine pH	111	6.6 ± 0.8	6.5 (6.0, 7.2)	−0.062	0.54	−0.085	0.44
Urine Osmolality, mOsm/kg of water	117	534.8 ± 201.2	491 (400, 625)	0.181	0.062	0.219	0.046
Urine volume, µL	120	826.4 ± 651.4	745.0 (285.0, 1210.0)	−0.126	0.19	−0.007	0.95
Urinary protein, mg/L	83	369.4 ± 321.7	255.6 (105.2, 570.4)	0.176	0.12	0.177	0.16
Urinary creatinine, mmol/L	83	0.3 ± 0.2	0.3 (0.3, 0.5)	0.183	0.11	0.228	0.07
Urinary protein: creatinine, mg/mmol	83	2080 ± 6530	789 (349, 1400)	0.121	0.29	0.112	0.37
Urinary total Na, ng	92	2415 ± 1526	2060 (1296, 3380)	0.006	0.95	0.121	0.31
Na excretion rate, ng/h	92	1208 ± 763	1030 (648, 1690)	−0.003	0.98	0.113	0.34
Urinary Na: creatinine, ng/mmol	82	10.3 ± 16.7	6.8 (4.8, 10.6)	−0.122	0.29	−0.128	0.31
Urinary total K, ng	92	1002 ± 698	876 (514, 1326)	0.045	0.68	0.115	0.34
K excretion rate, ng/h	92	501 ± 349	438 (257, 663)	0.020	0.85	0.078	0.52
Urinary K: creatinine, ng/mmol	82	3.7 ± 5.0	2.9 (2.1, 3.8)	−0.202	0.08	−0.249	0.045

^aNumber represents the number of successful mouse phenotype observes depending on the availability of the sample.

^bGene expression data were available for 95 mice.