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. 2020 May 8;10(7):2353–2364. doi: 10.1534/g3.120.401310

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Copyright © 2020 Evans, Andersen

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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A large-effect QTL on the center of chromosome V underlies responses to several chemotherapeutics. Linkage mapping results with the set 2 RIAILs for a representative trait for each drug are shown (amascrine: median.norm.EXT, bleomycin median.TOF:, bortezomib: median.TOF, carmustine: norm.n, cisplatin: median.TOF, etoposide: norm.n, puromycin: median.TOF, silver: median.TOF). Genomic position (x-axis) is plotted against the logarithm of the odds (LOD) score (y-axis) for 13,003 genomic markers. Each significant QTL is indicated by a red triangle at the peak marker, and a blue rectangle shows the 95% confidence interval around the peak marker. The percentage of the total variance in the RIAIL population that can be explained by each QTL is shown above the QTL. The dotted vertical line represents the genomic position of scb-1.