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. 2020 Jun 5;10(6):989. doi: 10.3390/ani10060989

Figure 2.

Figure 2

Percentage of studies that achieved either a low, unclear or high risk of bias for each domain using the SYstematic Review Centre for Laboratory animal Experimentation (SYRCLE) risk of bias tool. Although randomisation was mentioned in several articles, lack of reporting of the method used resulted in an unclear risk of bias for most items. Blinding was impossible to achieve due to the inherent nature of the study design.