Table 2.
Results of multivariable Cox proportional hazards regression model analysis.
| Univariable | Multivariable | |||
|---|---|---|---|---|
| HR (95% CI) | p value | HR (95% CI) | p value | |
| Age, years | 1.093 (1.032–1.157) | 0.002 | 1.071 (1.009–1.137) | 0.024 |
| Female | 0.629 | |||
| BSA (m2) | 0.315 | |||
| Systolic BP (mmHg) | 0.841 | |||
| Heart rate (beats/min) | 0.435 | |||
| Hemoglobin (g/dl) | 0.482 | |||
| Creatine (mg/dl) | 0.560 | |||
| Log BNP (pg/ml) | 2.120 (1.542–2.915) | <0.001 | 1.533 (1.090–2.156) | 0.014 |
| Tau (msec) | 1.061 (1.009–1.114) | 0.020 | 0.205 | |
| Peak + dP/dt (mmHg/sec) | 0.210 | |||
| Peak − dP/dt (mmHg/sec) | 1.001 (1.000–1.002) | 0.019 | 0.496 | |
| CI (l/min/m2) | 0.692 | |||
| LVEF (%) | 0.935 (0.891–0.982) | 0.007 | 0.249 | |
| LVEDVI (ml/m2) | 1.035 (1.013–1.058) | 0.002 | 0.351 | |
| LVESVI (ml/m2) | 1.059 (1.027–1.092) | <0.001 | 1.051 (1.011–1.093) | 0.013 |
| LVEDP (mmHg) | 0.084 | |||
| Hypertension | 0.305 | |||
| Diabetes | 0.356 | |||
| Hyperlipidemia | 0.874 | |||
| Past history of MI | 0.388 | |||
| ACEI and/or ARB | 0.456 | |||
| Beta blocker | 0.389 | |||
| CCB | 0.427 | |||
| Diuretic agent | 0.856 | |||
ACEI, angiotensin converting enzyme inhibitor; ARB, angiotensin receptor blocker; BP, blood pressure; BNP, brain natriuretic peptide; BSA, body surface area; CCB, calcium channel blocker; CI, cardiac index; dP/dt, the first derivative of left ventricular pressure; LVEF, left ventricular ejection fraction; LVEDP, left ventricular end-diastolic pressure; LVEDVI, left ventricular end-diastolic volume index; LVESVI, left ventricular end-systolic volume index; MI, myocardial infarction.