Table 2.
Group | Test Article | Dose/Eye | n and Sex | Sacrifice Day |
---|---|---|---|---|
1a | aflibercept | 1.2 mg | 1 M/1 F | 1 |
1b | aflibercept | 1.2 mg | 1 M/1 F | 7 |
1c | aflibercept | 1.2 mg | 1 M/1 F | 14 |
1d | aflibercept | 1.2 mg | 1 M/1 F | 28 |
1e | aflibercept | 1.2 mg | 1 M/1 F | 42 |
1f | aflibercept | 1.2 mg | 1 M/1 F | 56 |
2 | ADVM-022 | 2 × 1011 vg | 1 M/1 F | 56 |
3 | ADVM-022 | 6 × 1011 vg | 1 M/1 F | 56 |
4 | ADVM-022 | 2 × 1012 vg | 1 M/1 F | 56 |
F, female; M, male.