Figure 3.
Influence of soluble serum α-klotho on the association of eGFRcr with 1,25-(OH)2 vitamin D3 and on the association of body mass index with plasma phosphate. Multivariable regression models in Table 3 are visualized to illustrate the relationship between the explanatory variable of interest while holding the effect of all other covariables in the model constant. Solid lines represent regression lines. (A) Influence of soluble serum α-klotho on the association of eGFRcr with 1,25-(OH)2 vitamin D3. (B) Influence of soluble serum α-klotho on the association of body mass index with plasma phosphate. Study participants were divided into 3 equal-sized groups belonging to the nearest class of soluble serum α-klotho levels. BSA, body surface area; eGFRcr, creatinine-based CKD-EPI 2009 equation to estimate the glomerular filtration rate.