Table 2.
Potential key genes that are differentially expressed related to SF development.
| Gene | Description | log2 (Fold Change) | ||
|---|---|---|---|---|
| D135 vs. D105 | DR135 vs. D105 | DR135 vs. D135 | ||
| Wnt related | ||||
| SFRP2 | Secreted Frizzled Related Protein 2 | −2.40341 | −2.79309 | −0.38968 |
| SFRP4 | Secreted Frizzled Related Protein4 | −1.07911 | −2.10080 | −1.02169 |
| SFRP5 | Secreted Frizzled Related Protein5 | 1.45166 | 1.62546 | 0.17380 |
| WNT5A | Wnt Family Member 5A | −0.37882 | −0.51687 | −0.13805 |
| WNT2 | Wnt Family Member 2 | −1.14818 | −0.92800 | 0.22018 |
| DKK1 | Dickkopf-Related Protein 1 | −1.44226 | −1.56450 | −0.12224 |
| CCND1 | Cyclin D1 | −0.40895 | −0.70606 | −0.29711 |
| CSNK1E | Casein Kinase 1 Epsilon | 2.69495 | 2.67435 | −0.02060 |
| TGF-β/BMP | ||||
| BMP2 | Bone Morphogenetic Protein 2 | 1.10571 | 1.19215 | 0.08644 |
| BMP3 | Bone Morphogenetic Protein 3 | −0.57071 | −1.11402 | −0.54331 |
| BMP4 | Bone Morphogenetic Protein 4 | 0.78090 | 0.83946 | 0.05856 |
| BMP5 | Bone Morphogenetic Protein 5 | −2.48384 | −2.95107 | −0.46723 |
| TGF-β2 | Transforming Growth Factor Beta 2 | −0.73641 | −1.11444 | −0.37803 |
| TGF-β3 | Transforming Growth Factor Beta 3 | −0.33778 | −0.75208 | −0.41430 |
| BAMBI | BMP And Activin Membrane-Bound Inhibitor | 1.05036 | 1.55454 | 0.50418 |
| MYC | V-Myc Avian Myelocytomatosis Viral Oncogene Homolog | 0.57669 | 0.42712 | −0.14958 |
| Wool follicle development and transcriptional regulator genes | ||||
| PITX1 | Paired Like Homeodomain 1 | −2.93483 | −0.74502 | 2.18981 |
| CAV3 | Caveolin 3 | −3.14244 | −2.48249 | 0.65995 |
| SIX4 | SIX Homeobox 4 | −2.38845 | −1.90240 | 0.48605 |
| SLURP1 | Secreted LY6/PLAUR Domain Containing 1 | 4.00780 | 3.56769 | −0.44011 |
| GATA3 | GATA Binding Protein 3 | 0.71200 | 0.40038 | −0.31162 |
| EDAR | Ectodysplasin A Receptor | −0.91182 | −1.05320 | −0.14137 |
| FOXN1 | Forkhead Box N1 | 2.21443 | 1.85361 | −0.36083 |
| HOXC13 | Homeobox C13 | 0.69009 | 0.73500 | 0.04492 |
| LGR5 | Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 | 0.85120 | 0.84652 | −0.00468 |
| MSX2 | Msh Homeobox 2 | 0.36489 | 0.65509 | 0.29020 |
| DNASE1L2 | Deoxyribonuclease 1 Like 2 | 1.55896 | 2.07115 | 0.51219 |
| VDR | Vitamin D Receptor | 1.10678 | 0.95640 | −0.15039 |
| IGFBP3 | Insulin-Like Growth Factor Binding Protein 3 | 0.17093 | −0.45424 | −0.62518 |
| Branching morphology related genes | ||||
| PITX2 | Paired Like Homeodomain 2 | −3.06724 | −3.39049 | −0.32325 |
| MMP12 | Matrix Metallopeptidase 12 | 3.74146 | 3.73938 | −0.00208 |
| IGF1 | Insulin-Like Growth Factor 1 | −0.71163 | −0.75344 | −0.04181 |
| SOX9 | SRY-Box 9 | 0.95372 | 0.63590 | −0.31782 |
| FOXA1 | Forkhead Box A1 | 2.24977 | 2.56852 | 0.31876 |
| Keratin differentiation-related genes | ||||
| KRT16 | Keratin 16 | 1.27650 | −1.44261 | −2.71911 |
| KRTAP8-1 | Keratin Associated Protein 8-1 | 4.37327 | 4.93892 | 0.56566 |
| KRT13 | Keratin 13 | −7.51172 | −6.59676 | 0.91496 |
| KRT78 | Keratin 78 | −2.72411 | −2.20584 | 0.51827 |