Table 1.
Microbial Composition at the Phyla Level in GH-/- Mice, bGH Mice, and their Respective Littermate Controls
| Decreased GH Action | Increased GH Action | |||||
|---|---|---|---|---|---|---|
| Phylum | WT | GH-/- | Effect size | WT | bGH | Effect size |
| Firmicutes | 59.8% | 58.7% | 0.07 | 58.1% | 49.2% | 0.73 |
| Bacteroidetes | 28.8% | 36.1% | 0.44 | 31.0% | 37.9% | 0.61 |
| Proteobacteria | 4.14% | 1.73%* | 1.66 | 3.93% | 4.66% | 0.21 |
| Actinobacteria | 0.12% | 0.10% | 0.10 | 2.43% | 2.68% | 0.08 |
| Campylobacterota | 6.11% | 2.55%* | 1.65 | 1.79% | 2.10% | 0.10 |
| Cyanobacteria | 0.35% | 0.33% | 0.04 | 0.64% | 0.96% | 0.16 |
| Deferribacteres | 0.02% | 0.02% | 0.03 | 0.01% | 0.11%* | 0.96 |
*indicates statistical significance. Effect size was calculated by Cohen d between each mouse line and their respective littermate control group.