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. 2020 Jul 8;20:274. doi: 10.1186/s12883-020-01848-4

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Factors associated with insufficient response in backward logistic regression analysis. Variables included in the logistic model but not found to be significant included age, sex, employment status, time to migraine diagnosis (in weeks), living status, smoking status, comorbidities (depression, anxiety, cardiovascular disease), insurance plan, currently prescribed acute medication, migraine with aura, change in migraine headache days per month before prescribed acute treatment, migraine headache days per month, number of prescribed acute medications, and number of prescribed prophylaxis therapies. Odds ratio > 1 with 95% CI not crossing 1 indicates a significant factor associated with an insufficient response to acute treatment; odds ratio < 1 with 95% CI not crossing 1 indicates a significant factor for a response to acute treatment. Cardiovascular disease includes angina, hypertension, ischemic heart disease, post myocardial infarction, and congestive heart failure. CI confidence interval; MIDAS Migraine Disability Assessment