Table 1.
Demographic, epidemiologic and clinical characteristics of different subtypes in patients with COVID-19
| Characteristic | Mild type (n = 52) | Common type (n = 658) | Severe type (n = 61) | Critical type (n = 17) | Pvalue |
|---|---|---|---|---|---|
| Age (years) | 37.5 (19.3–45.8) | 45.0 (35.0–55.0) | 55.0 (44.0–62.0) | 70.0 (55.0–73.0) | < 0.001 |
| Distribution | < 0.001 | ||||
| ≤ 18 | 12 (23.1) | 9 (1.4) | 0 (0.0) | 0 (0.0) | |
| 19–40 | 16 (30.8) | 241 (36.6) | 11 (18.0) | 0 (0.0) | |
| 41–65 | 24 (46.2) | 350 (53.2) | 39 (63.9) | 7 (41.2) | |
| ≥ 66 | 0 (0.0) | 58 (8.8) | 11 (18.0) | 10 (58.8) | |
| Sex (male) | 26 (50.0) | 329 (50.0) | 39 (63.9) | 13 (76.5) | 0.034 |
| BMI (kg/m2) | < 0.001 | ||||
| < 18.5 | 5/25 (20.0) | 20/370 (5.4) | 0/36 (0.0) | 0/13 (0.0) | |
| 18.5–< 25 | 17/25 (68.0) | 240/370 (64.9) | 17/36 (47.2) | 7/13 (53.8) | |
| ≥ 25 | 3/25 (12.0) | 110/370 (29.7) | 19/36 (52.8) | 6/13 (46.2) | |
| Current smoker | 2 (3.8) | 45 (6.8) | 5 (8.2) | 2 (11.8) | 0.544 |
| Exposure history in Wuhan | 23 (44.2) | 331 (50.3) | 31 (50.8) | 8 (47.1) | 0.853 |
| Incubation period (days) | 7.0 (3.0–11.5) (n = 17) | 6.0 (3.0–9.0) (n = 156) | 3.0 (2.0–5.5) (n = 14) | 7.0 (n = 1) | 0.239 |
| Family cluster | 25 (48.1) | 152 (23.1) | 11 (18.0) | 7 (41.2) | < 0.001 |
| Time from illness onset to first hospital admission (days) | 2.5 (1.0–4.0) | 3.0 (1.0–6.0) | 5.0 (2.0–8.0) | 5.0 (2.5–6.5) | < 0.001 |
| Coexisting disorder | |||||
| Any | 10 (19.2) | 161 (24.5) | 31 (50.8) | 16 (94.1) | < 0.001 |
| Hypertension | 5 (9.6) | 87 (13.2) | 19 (31.1) | 15 (88.2) | < 0.001 |
| Heart disease | 0 (0.0) | 9 (1.4) | 1 (1.6) | 1 (5.9) | 0.254 |
| Diabetes | 3 (5.8) | 42 (6.4) | 8 (13.1) | 4 (23.5) | 0.019 |
| Chronic obstructive pulmonary disease | 0 (0.0) | 0 (0.0) | 2 (3.3) | 1 (5.9) | 0.001 |
| Cancer | 0 (0.0) | 3 (0.5) | 3 (4.9) | 0 (0.0) | 0.030 |
| Chronic liver disease | 1 (1.9) | 26 (4.0) | 2 (3.3) | 2 (11.8) | 0.351 |
| Chronic renal disease | 0 (0.0) | 5 (0.8) | 1 (1.6) | 1 (5.9) | 0.150 |
| Symptoms on admission | |||||
| Fever | 28 (53.8) | 534 (81.2) | 57 (93.4) | 17 (100.0) | < 0.001 |
| Cough | 19 (36.5) | 426 (64.7) | 49 (80.3) | 12 (70.6) | < 0.001 |
| Sputum production | 8 (15.4) | 219 (33.3) | 29 (47.5) | 9 (52.9) | 0.001 |
| Hemoptysis | 0 (0.0) | 8 (1.2) | 6 (9.8) | 1 (5.9) | 0.001 |
| Sore throat | 8 (15.4) | 95 (14.4) | 7 (11.5) | 1 (5.9) | 0.796 |
| Nasal obstruction | 6 (11.5) | 41 (6.2) | 0 (0.0) | 0 (0.0) | 0.034 |
| Myalgia | 4 (7.7) | 68 (10.3) | 14 (23.0) | 5 (29.4) | 0.004 |
| Fatigue | 10 (19.2) | 105 (16.0) | 18 (29.5) | 6 (35.3) | 0.013 |
| Gastrointestinal symptom | 7 (13.5) | 63 (9.6) | 12 (19.7) | 6 (35.3) | 0.002 |
| Headache | 2 (3.8) | 61 (9.3) | 11 (18.0) | 1 (5.9) | 0.076 |
Data are presented as medians (interquartile ranges, IQR), n (%) and n/N (%)