Table 2.
Laboratory and radiograph findings of different subtypes in patients with COVID-19 on admission
| Variable | Mild type (n = 52) | Common type (n = 658) | Severe type (n = 61) | Critical type (n = 17) | Pvalue |
|---|---|---|---|---|---|
| Blood routine | |||||
| Leucocyte count (× 109/L) | 5.7 (4.3–7.1) | 4.7 (3.8–5.8) | 4.9 (3.8–6.6) | 6.8 (3.8–8.8) | 0.002 |
| < 4 | 9 (17.3) | 201 (30.5) | 19 (31.1) | 5 (29.4) | |
| > 10 | 1 (1.9) | 10 (1.5) | 4 (6.6) | 3 (17.6) | |
| Neutrophil count (× 109/L) | 3.6 (2.0–5.0) | 2.9 (2.2–3.8) | 3.2 (2.6–5.0) | 5.8 (2.8–8.0) | < 0.001 |
| > 7 | 3 (5.8) | 17 (2.6) | 7 (11.5) | 7 (41.2) | |
| Lymphocyte count (× 109/L) | 1.3 (1.1–1.9) | 1.2 (0.9–1.6) | 0.9 (0.6–1.2) | 0.5 (0.4–0.8) | < 0.001 |
| < 0.8 | 8 (15.4) | 91 (13.8) | 23 (37.7) | 12 (70.6) | |
| Hemoglobin (g/L) | 139.0 (131.0–152.0) | 138.0 (127.0–150.0) | 139.0 (122.5–153.0) | 128.0 (117.0–153.5) | 0.332 |
| Platelets count (×109/L) | 206.0 (171.0–241.3) | 180.0 (147.8–221.3) | 172.0 (138.0–214.0) | 146.0 (122.0–181.5) | 0.001 |
| < 100 | 0 (0.0) | 23 (3.5) | 2 (3.3) | 2 (11.8) | |
| Coagulation function | |||||
| International normalized ration (INR) | 1.0 (1.0–1.1) | 1.0 (1.0–1.1) | 1.0 (1.0–1.1) | 1.0 (1.0–1.2) | 0.070 |
| Blood biochemistry | |||||
| Albumin (ALB, g/L) | 42.5 (40.5–45.7) | 41.7 (38.7–43.9) | 38.7 (35.8–41.6) | 35.9 (30.8–37.6) | < 0.001 |
| Alanine aminotransferase (ALT, U/L) | 20.0 (12.0–39.1) | 21.1 (15.0–33.0) | 24.0 (16.5–34.5) | 20.5 (14.0–30.8) | 0.528 |
| Aspartate aminotransferase (AST, U/L) | 22.0 (16.5–34.0) | 25.0 (19.1–32.2) | 28.0 (22.0–40.0) | 30.5 (25.0–41.8) | 0.002 |
| > 40 | 7 (13.5) | 76 (11.6) | 13 (21.3) | 5 (29.4) | |
| Total bilirubin (TB) (μmol//L) | 8.8 (6.2–11.6) | 9.5 (7.0–13.1) | 10.7 (7.8–15.6) | 10.3 (8.0–14.6) | 0.205 |
| Potassium (mmol/L) | 3.8 (3.6–4.2) | 3.8 (3.6–4.1) | 3.9 (3.6–4.2) | 3.7 (3.2–3.9) | 0.112 |
| Sodium (mmol/L) | 139.0 (138.0–141.0) | 138.5 (136.3–140.2) | 137.4 (135.0–139.3) | 136.0 (130.1–137.8) | < 0.001 |
| Blood urea nitrogen (BUN, mmol/L) | 4.2 (3.2–4.7) | 3.7 (3.0–4.6) | 4.0 (3.2–5.6) | 5.8 (3.6–12.3) | 0.001 |
| Creatinine (CR, μmol/L) | 66.0 (58.0–76.0) | 65.3 (55.0–78.0) | 71.0 (62.5–80.5) | 79.0 (65.9–106.5) | 0.002 |
| Creatinine kinase (CK, U/L) | 60.5 (42.5–75.3) | 68.5 (47.0–105.3) | 76.0 (56.5–120.5) | 146.0 (54.3–255.5) | < 0.001 |
| Lactate dehydrogenase (LDH, U/L) | 175.0 (147.0–241.0) | 207.5 (168.0–254.0) | 272.0 (221.5–366.5) | 320.5 (256.3–356.5) | < 0.001 |
| > 250 | 11 (21.2) | 167 (25.4) | 39 (63.9) | 13 (76.5) | |
| Infection-related biomarkers | |||||
| C-reactive protein (CRP, mg/L) | 1.9 (0.5–5.5) | 7.7 (2.5–19.4) | 26.2 (10.4–51.1) | 45.5 (14.7–84.9) | < 0.001 |
| Procalcitonin (PCT, ng/ml) | 0.1 (0.0–0.1) | 0.1 (0.0–0.1) | 0.1 (0.0–0.1) | 0.1 (0.0–0.2) | 0.013 |
| Chest x-ray/CT finding | |||||
| Multiple mottling and ground-glass opacity | 0(0.0) | 183(27.8) | 37 (60.7) | 15 (88.2) | < 0.001 |
Data are presented as medians (interquartile ranges, IQR), n (%) and n/N (%)