Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jul 7;11:3383. doi: 10.1038/s41467-020-17205-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 4 — a Genome-wide coverage plots at all, SHARED, IRI-decreased and IRI-increased enhancers. The coverage for HNF4A and GR decreased in SHARED and IRI-decreased enhancer group after IRI. In contrast, STAT3 shows increased coverage at IRI-increased enhancers. STAT5 peak height at enhancer elements is unchanged after kidney injury. b Representative examples of transcription factor binding at enhancer sites in kidney epithelia cells. The Slc34a1 and Junb genomic locus are shown for HNF4A, GR, STAT3, and STAT5 binding together with H3K4me3 and H3K27ac in the SHAM (left) and IRI (right) condition. Enhancer elements are indicated by gray bars.