Table 1.
Genes differentially expressed between CD56+ and CD146+ BMSC subsets from OA femoral head bone.
| Gene symbol | Gene name | Fold difference | p value* |
|---|---|---|---|
| SPP1 | Secreted phosphoprotein 1 (osteopontin) | 508.62 | 0.0045 |
| CHAD | Chondroadherin | 221.22 | 0.0045 |
| BGLAP | Bone gamma-carboxyglutamate protein (osteocalcin) | 163.11 | 0.0016 |
| OMD | Osteomodulin | 86.02 | 0.0047 |
| WIF1 | WNT inhibitory factor 1 | 80.85 | 0.0045 |
| SFRP4 | Secreted frizzled-related protein 4 | 40.36 | 0.0133 |
| SP7 | Sp7 transcription factor | 25.78 | 0.0140 |
| TNFRSF11B | Tumour necrosis factor receptor superfamily, member 11b (osteoprotegerin) | 15.53 | 0.0342 |
| RUNX2 | Runt-related transcription factor 2 | 13.57 | 0.0117 |
| BAMBI | BMP and activin membrane-bound inhibitor homolog | 11.75 | 0.0133 |
| PDGFRA | Platelet-derived growth factor receptor, alpha polypeptide | 10.31 | 0.0342 |
| FGFR3 | Fibroblast growth factor receptor 3 | 8.12 | 0.0047 |
| CDH11 | Cadherin 11, type 2, OB-cadherin | 6.93 | 0.0342 |
| TWIST1 | Twist homolog 1 | 6.91 | 0.0133 |
| BMPR1A | Bone morphogenetic protein receptor, type IA | 6.20 | 0.0047 |
| FZD8 | Frizzled homolog 8 | 6.01 | 0.0342 |
| FGFR1 | Fibroblast growth factor receptor 1 | 5.07 | 0.0047 |
| NOG | Noggin | 3.82 | 0.0047 |
| FZD7 | Frizzled homolog 7 | 3.62 | 0.0133 |
| ALPL | Alkaline phosphatase | 2.78 | 0.0342 |
| PPARG | Peroxisome proliferator-activated receptor gamma | 0.38 | 0.0133 |
| GATA2 | GATA binding protein 2 | BD in CD56 | NA |
* Friedman test for the donor matched samples with the Bonferroni–Dunn correction for multiple-group comparisons. BD below detection, NA not available.